Skip to Content
Home > Wellness > Health Library > Typical Smallpox Vaccine Reaction
Browse and register for related classes.
Source: U.S. Centers for Disease Control and Prevention (CDC).
Available online: http://www.bt.cdc.gov
The pictures show a typical reaction to the smallpox vaccine. First, a small bump (papule) forms at the vaccine site 3 to 5 days after vaccination. This becomes a pus-filled area (pustule) a few days later. The pustule dries up and then forms a scab by about 14 days after vaccination. The scab finally falls off at about 21 days after vaccination.
ByHealthwise StaffPrimary Medical ReviewerE. Gregory Thompson, MD - Internal MedicineSpecialist Medical ReviewerChristine Hahn, MD - Epidemiology
Current as ofMay 24, 2016
Current as of:
May 24, 2016
E. Gregory Thompson, MD - Internal Medicine & Christine Hahn, MD - Epidemiology
To learn more about Healthwise, visit Healthwise.org.
© 1995-2016 Healthwise, Incorporated. Healthwise, Healthwise for every health decision, and the Healthwise logo are trademarks of Healthwise, Incorporated.
Feeling under the weather?
Use our interactive symptom checker to evaluate your symptoms and determine appropriate action or treatment.
250 Pleasant Street
Concord, NH 03301
Share Feedback and Questions
View Quality Data
© 2017 Concord Hospital