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Myelodysplastic syndromes (MDS) are a group of blood diseases that
cause an abnormally low production of blood cells. MDS is more common in older
adults and rare in children and may develop before the start of a more serious
blood disease, acute myelogenous leukemia.
Symptoms of MDS include a decreased production of red blood cells
(anemia) and bleeding caused by a decreased production of platelet cells
(thrombocytopenia). Later symptoms include enlargement of the liver
(hepatomegaly), enlargement of the spleen (splenomegaly), and swelling of the
lymph nodes (lymphadenopathy).
Treatment of MDS depends on the severity of the disease and can
include blood transfusions and chemotherapy.
Current as of:
November 20, 2015
E. Gregory Thompson, MD - Internal Medicine & Brian Leber, MDCM, FRCPC - Hematology
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